ABSTRACT
BACKGROUND: Epilepsia partialis continua (EPC) is an uncommon condition with several different etiological causes. In this article, we presented a case of EPC due to COVID-19 infection. CASE REPORT: A 77-year-old woman with diabetes, asthma, hypertension, and chronic renal failure went to the emergency room with shortness of breath. The patient was awake and had slight hemiparesis sequela on the left due to a cerebrovascular incident 20 years earlier on neurological assessment. Non-contrast thorax computed CT revealed patchy ground-glass alveolo-acinar density increases in bilateral lung subzones, confirming COVID-19 pneumonia. After getting a positive COVID-19 PCR test, the patient was admitted to the department of infectious diseases. After a week in the hospital, seizures involving the right arm, leg, and part of the face appeared. The patient could not respond to questions. The patient's seizures lasted 12-24 hours. EEG was compatible with Epilepsia partialis continua. The cerebrospinal fluid examination was normal. Both clinical and EEG findings of the patient improved with treatment. CONCLUSIONS: Several causes may contribute to the onset of Epilepsia partialis continua. COVID-19 infection might be one of the etiological explanations for the diagnosis of Epilepsia partialis continua and the prognosis may be very good too.